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Product Name phospho-IL3RB (Tyr593) Chinese Name 磷酸化白细胞介素3受体β抗体 Alias IL3RB (phospho Y593); p-IL3RB (phospho Y593); CD131; CDw131; Colony stimulating factor 2 receptor beta; Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage); Csf2rb; Cytokine receptor common beta chain; Cytokine receptor common beta chain precursor (CDw131 antigen); Cytokine receptor common subunit beta; GM CSF/IL 3/IL 5 receptor common beta chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; IL3RB; IL3RB_HUMAN; IL5RB; Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity); stimulating factor 3 receptor, beta (high affinity). Product Type Phosphorylated anti Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 97kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthesised acetylpeptide derived from human IL3RB around the acetylation site of Tyr593: GP(p-Y)LG Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function:
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Subcellular Location:
Membrane.
Similarity:
Belongs to the type I cytokine receptor family.
Type 4 subfamily.
Contains 2 fibronectin type-III domains.
SWISS:
P32927
Gene ID:
1439
Database links:Entrez Gene: 1439 Human
Entrez Gene: 12983 Mouse
Entrez Gene: 12984 Mouse
Omim: 138981 Human
SwissProt: P32927 Human
SwissProt: P26955 Mouse
Unigene: 285401 Human
Unigene: 592192 Human
Unigene: 235324 Mouse
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