Product Name	HSPA1L
Chinese Name	热休克蛋白70样蛋白抗体
Alias	Heat shock 70 kDa protein 1 Hom; Heat shock 70 kDa protein 1 like; Heat shock 70 kDa protein 1-Hom; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70kD protein like 1; HS71L_HUMAN; HSP70 1L; HSP70 HOM; HSP70-Hom; HSPA1L; hum70t; Spermatid specific heat shock protein 70.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Sheep, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	70kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HSPA1L: 501-600/641
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008] Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Tissue Specificity: Expressed in spermatids. Similarity: Belongs to the heat shock protein 70 family. SWISS: P34931 Gene ID: 3305 Database links: Entrez Gene: 540190 Cow Entrez Gene: 3305 Human Entrez Gene: 15482 Mouse Entrez Gene: 100144518 Pig Entrez Gene: 24963 Rat Entrez Gene: 779883 Xenopus tropicalis Omim: 140559 Human SwissProt: P0CB32 Cow SwissProt: P34931 Human SwissProt: P16627 Mouse SwissProt: A5A8V7 Pig SwissProt: P55063 Rat Unigene: 690634 Human Unigene: 14287 Mouse Unigene: 187184 Rat

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