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Product Name MSL1v1/CENP36 Chinese Name 着丝粒蛋白36抗体 Alias CENP-36; centromere protein 36; DKFZp686P06109; DKFZp727C091; hypothetical protein LOC284058; K1267_HUMAN; KIAA1267; male-specific lethal 1 homolog; MGC102843; MLL1/MLL complex subunit KIAA1267; MSL1v1; NSL1. Research Area Cell biology immunology Developmental biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 121kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MSL1v1/CENP36: 501-600/1105 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]
Function:
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
Subcellular Location:
Expressed in the brain.
Tissue Specificity:
Expressed in the brain.
SWISS:
Q7Z3B3
Gene ID:
284058
Database links:Entrez Gene: 284058 Human
Entrez Gene: 76719 Mouse
SwissProt: Q7Z3B3 Human
SwissProt: Q80TG1 Mouse
Unigene: 648744 Human
Unigene: 136418 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (Rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MSL1v1) Polyclonal Antibody, Unconjugated (SL17857R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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