Product Name	MRPL22
Chinese Name	Mitochondrion核糖体蛋白L22抗体
Alias	39S ribosomal protein L21; 39S ribosomal protein L21, mitochondrial; 39S ribosomal protein L21, mitochondrial precursor; L21mt; MGC62013; mitochondrial; Mitochondrial ribosomal protein L21; MRP L21; MRP-L21; Mrpl21; RM21_HUMAN.
Research Area	Cell biology  immunology  transcriptional regulatory factor  Mitochondrion  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Chicken, Zebrafish, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MRPL22: 41-120/206
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein L22P family. SWISS: Q9NWU5 Gene ID: 29093 Database links: Entrez Gene: 29093 Human Entrez Gene: 216767 Mouse Entrez Gene: 287302 Rat Omim: 611835 Human SwissProt: Q9NWU5 Human SwissProt: Q8BU88 Mouse SwissProt: P0C2C0 Rat Unigene: 483924 Human Unigene: 259907 Mouse Unigene: 13421 Rat
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-MRPL22 (SL17781R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 23 kD

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