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Rabbit Anti-MRPL13 antibody
Rabbit Anti-MRPL13 antibody
39S ribosomal protein L13, mitochondrial; L13; L13A; L13mt; Mitochondrial ribosomal protein L13; MRP L13; OTTHUMP00000228247; OTTHUMP00000228248; RPL13; RPML13.
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  • NO.:SL17769R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name MRPL13
Chinese Name Mitochondrion核糖体蛋白L13抗体
Alias 39S ribosomal protein L13, mitochondrial; L13; L13A; L13mt; Mitochondrial ribosomal protein L13; MRP L13; OTTHUMP00000228247; OTTHUMP00000228248; RPL13; RPML13.  
Research Area Cell biology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 21kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MRPL13: 21-120/178 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Function:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [Entrez Gene]

Subunit:
Interacts with OXA1L.

Subcellular Location:
Mitochondrion

Similarity:
Belongs to the ribosomal protein L13P family.

SWISS:
Q9BYD1

Gene ID:
28998

Database links:

Entrez Gene: 617901 Cow

Entrez Gene: 482029 Dog

Entrez Gene: 28998 Human

Entrez Gene: 68537 Mouse

Entrez Gene: 299938 Rat

Entrez Gene: 553555 Zebrafish

Omim: 610200 Human

SwissProt: Q3SYS1 Cow

SwissProt: Q9BYD1 Human

SwissProt: Q9D1P0 Mouse

Unigene: 333823 Human



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MRPL13) Polyclonal Antibody, Unconjugated (SL17769R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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