Product Name	MRGPRA
Chinese Name	腺嘌呤受体抗体
Alias	Adenine receptor; G protein coupled receptor rc 56 1 3; Mas related G protein coupled receptor member A; Mas related gene A; MGC108580; Mrg A; Mrga 10; MrgA; Mrgpra; Nuclear receptor MrgA10 RF amide G protein coupled receptor.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from rat MRGPRA: 1-100/304 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MRGPRA, Mas-related G-protein coupled receptor member A, is an orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. It mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins and it may regulate the function of nociceptive neurons by modulation of pain perception. Function: ] Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons. Similarity: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons. SWISS: Q7TN49 Gene ID: 252960 Database links: Entrez Gene: 252960 Rat SwissProt: Q7TN49 Rat
Product Picture	Sample: Liver (Mouse) Lysate at 40 ug Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-MRGPRA (SL17756R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD

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