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Product Name MRFAP1 Chinese Name Tlymphocyte活化蛋白MRFAP1抗体 Alias Mof4 family associated protein 1; MORF4 family associated protein 1; OTTHUMP00000155159; OTTHUMP00000217763; PAM14; PGR1; Protein associated with MRG 14 kDa; Protein associated with MRG of 14 kDa; Protein PGR1; T cell activation protein. Research Area Tumour Cell biology immunology t-lymphocyte Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 15kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MRFAP1: 51-127/127 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Function:
MRFAP1 is found in a complex composed of MORF4L1, MRFAP1 and RB1. It interacts via its N-terminus with MORF4L1. It also interacts with CSTB and MORF4L2.
Subcellular Location:
Nucleus. Cytoplasm; perinuclear region. Note: Colocalizes with MORF4L1 to cell nuclei.
Similarity:
Belongs to the MORF4 family-associated protein family.
SWISS:
Q9Y605
Gene ID:
93621
Database links:Entrez Gene: 93621 Human
Entrez Gene: 545208 Mouse
SwissProt: Q9Y605 Human
SwissProt: Q9CQL7 Mouse
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