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Rabbit Anti-MOGAT2 antibody
Rabbit Anti-MOGAT2 antibody
2 acylglycerol O acyltransferase 2; 2-acylglycerol O-acyltransferase 2; Acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5; Diacylglycerol acyltransferase 2 like protein 5; Diacylglycerol acyltransferase
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Details

Product Name MOGAT2
Chinese Name MOGAT2蛋白抗体
Alias 2 acylglycerol O acyltransferase 2; 2-acylglycerol O-acyltransferase 2; Acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5; Diacylglycerol acyltransferase 2 like protein 5; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O acyltransferase candidate 5; Diacylglycerol O-acyltransferase candidate 5; EC 2.3.1.22; FLJ22644; hDC5; hMGAT2; Mgat1l; MGAT2; MGC119183; MGC119184; MGC119185; MGC189143; mogat2; MOGT2_HUMAN; Monoacylglycerol O acyltransferase 1 like; Monoacylglycerol O acyltransferase 2; Monoacylglycerol O-acyltransferase 2.  
Research Area Tumour  Cell biology  Signal transduction  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MOGAT2: 51-150/334 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC 2.3.1.22) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 [PubMed 12621063]).[supplied by OMIM, Mar 2008]

Function:
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in liver, small intestine, colon, stomach and kidney.

Similarity:
Belongs to the diacylglycerol acyltransferase family.

SWISS:
Q3SYC2

Gene ID:
80168

Database links:

Entrez Gene: 80168 Human

Entrez Gene: 233549 Mouse

Entrez Gene: 681211 Rat

Omim: 610270 Human

SwissProt: Q3SYC2 Human

SwissProt: Q80W94 Mouse

Unigene: 288568 Human

Unigene: 208030 Mouse

Unigene: 19175 Rat



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