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Product Name SPATA15/SPATC1 Chinese Name 精子发生相关蛋白15抗体 Alias 1700084J23Rik; MGC144830; MGC61633; SPATA15; Spatc1; SPERI_HUMAN; Speriolin; Spermatogenesis and centriole associated 1; Spermatogenesis and centriole-associated protein 1; Spermatogenesis-associated protein 15; Spermatogenic cell specific Cdc20 binding protein; Spermatogenic cell-specific Cdc20-binding protein. Research Area Cell biology Developmental biology Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 62kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPATA15/SPATC1: 1-100/591 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SPATA15 is a 591 amino acid cytoplasmic protein expressed in testis that is part of a complex that includes p55 CDC, Cdc27. The gene encoding Speriolin is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Subunit:
Found in a complex with CDC20, CDC27 and TUBG1. Interacts with CDC20 (By similarity).
Subcellular Location:
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Colocalizes with the centrosomal pericentrin protein PCNT1.
Tissue Specificity:
Detected only in testis.
SWISS:
Q76KD6
Gene ID:
375686
Database links:Entrez Gene: 375686 Human
Entrez Gene: 74281 Mouse
Omim: 610874 Human
SwissProt: Q76KD6 Human
SwissProt: Q148B6 Mouse
Unigene: 97726 Human
Product Picture Sample: Heart (Mouse) Lysate at 40 ug
Primary: Anti-SPATA15/SPATC1(SL17636R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62kD
Observed band size: 62kD
Sample: Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-SPATA15/SPATC1(SL17636R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62kD
Observed band size: 62kD
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