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Product Name SPATA9 Chinese Name 精子发生相关蛋白9抗体 Alias FLJ35906; NYD SP16; spermatogenesis associated 9; Spermatogenesis associated protein 9; Testis development protein NYD SP16. Research Area Cell biology immunology Developmental biology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Pig, Cow, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 29kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPATA9: 121-200/254 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SPATA9 is a 254 amino acid single-pass membrane protein that is highly expressed in testis and pancreas with low expression in heart, lung, and brain. A component of the sperm acrosome, SPATA9 may participate in sperm capacitation and acrosome reaction, and is therefore necessary for fertilization. SPATA9 is also suggested to be involved in testicular development/spermatogenesis and may be an important factor in male infertility. No expression of SPATA9 was found in patients affected by Sertoli-cell-only syndrome, also known as Del Castillo syndrome or germ cell aplasia, which is characterized by male sterility without sexual abnormality. SPATA9 is encoded by a gene located on human chromosome 5, which consists of about 181 million base pairs, encodes around 1,000 genes and represents about 6% of human genomic DNA.
Function:
SPATA9 may play a role in testicular development/spermatogenesis and may be an important factor in male infertility. Three named isoforms exist.
Subcellular Location:
Membrane; Single-pass membrane protein
SWISS:
Q9BWV2
Gene ID:
83890
Database links:Entrez Gene: 83890 Human
Omim: 608039 Human
SwissProt: Q9BWV2 Human
Product Picture Sample: Testis (Mouse) Lysate at 40 ug
Primary: Anti-SPATA9 (SL17635R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 19 kD
Sample: Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-SPATA9 (SL17635R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 19 kD
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