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Product Name SPATA24 Chinese Name 精子发生相关蛋白24抗体 Alias 2700012K08Rik; 4930583E11Rik; 5133400G04Rik; AU016220; CCDC161; Coiled coil domain containing 161; SPA24_HUMAN; SPATA24; Spermatogenesis associated 24; Spermatogenesis associated protein 24; Spermatogenesis-associated protein 24; T6441; TATA binding protein like factor interacting protein; Testis protein T6441 homolog; TIPT; TIPT2; TLF interacting protein. Research Area Cell biology Developmental biology Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPATA24: 81-150/205 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis.
Function:
Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).
Subunit:
Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).
Subcellular Location:
Cytoplasm. Nucleus > nucleolus. Nucleus > nucleoplasm. Associated with chromatin.
Similarity:
Belongs to the SPATA24 family.
SWISS:
Q86W54
Gene ID:
202051
Database links:Entrez Gene: 202051 Human
SwissProt: Q86W54 Human
Unigene: 373612 Human
Unigene: 136857 Rat
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