Product Name	SPAG11A
Chinese Name	精子相关抗原11A抗体
Alias	EP2; 9230111C08Rik; Bin1b; EDDM2A; EP2; EP2e; EP2Q; He2; Human epididymis-specific protein 2; Protein EP2; SG11A_HUMAN; Spag11; SPAG11A; Sperm antigen HE2; Sperm-associated antigen 11A.
Research Area	Cell biology  immunology  Developmental biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Monkey, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	11kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPAG11A: 31-100/123
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SPAG11A is a 103 amino acid precursor protein that exists as four alternatively spliced isoforms, designated EP2A, EP2B, EP2C and EP2D, all of which are androgen-dependent, epididymis-specific secretory proteins that may play a role in sperm maturation and overall function. The gene encoding the SPAG11B precursor maps to a region on chromosome 8 that is near the ∫-defensin gene cluster and it is suggested that SPAG11B may exhibit functional characteristics (such as antimicrobial activity) that are similar to ∫-defensins. Human chromosome 8, on which the SPAG11B gene is localized, consists of nearly 146 million base pairs and houses more than 800 genes, some of which are associated with a variety of diseases and malignancies. Subcellular Location: Secreted. Similarity: Belongs to the SPAG11 family. SWISS: Q6PDA7 Gene ID: 653423 Database links: Entrez Gene: 653423 Human SwissProt: P43116 Human SwissProt: Q6PDA7 Human Unigene: 2717 Human

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