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Product Name OXA1L Chinese Name OXA1L蛋白抗体 Alias HSA; Mitochondrial inner membrane protein OXA1L; OXA1; OXA1 like protein; OXA1-like protein; OXA1Hs; Oxa1l; OXA1L_HUMAN; Oxidase (cytochrome c) assembly 1 like; Oxidase assembly 1 like protein; Oxidase assembly 1-like protein. Research Area Cell biology Signal transduction Cell type markers Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 49kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OXA1L: 301-400/435 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the OXA1/ALB3/YidC family.
SWISS:
Q15070
Gene ID:
5018
Database links:
Entrez Gene: 100719154 Guinea pig
Entrez Gene: 100056354 Horse
Entrez Gene: 5018 Human
Entrez Gene: 69089 Mouse
Entrez Gene: 562963 Zebrafish
Omim: 601066 Human
SwissProt: Q15070 Human
SwissProt: Q8BGA9 Mouse
Unigene: 151134 Human
Unigene: 182340 Mouse
Product Picture Sample:
Hcclm3(Human) Cell Lysate at 30 ug
Primary: Anti-OXA1L (SL17574R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 49 kD
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OXA1L) Polyclonal Antibody, Unconjugated (SL17574R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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