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Product Name INSL6 Chinese Name 胰岛素样肽6抗体 Alias Insl6; INSL6_HUMAN; Insulin-like peptide 6; Insulin-like peptide INSL6 A chain; Relaxin/insulin-like factor 1. Research Area Cell biology Developmental biology Signal transduction Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 22kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human INSL6: 21-100/213 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization. [provided by RefSeq, Jul 2008]
Function:
May have a role in sperm development and fertilization.
Subcellular Location:
Secreted.
Tissue Specificity:
Testis specific.
Similarity:
Belongs to the insulin family.
SWISS:
Q9Y581
Gene ID:
11172
Database links:Entrez Gene: 11172 Human
Omim: 606414 Human
SwissProt: Q9Y581 Human
Unigene: 632648 Human
Product Picture Tissue/cell: Rat testis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-INSL6 Polyclonal Antibody, Unconjugated(SL16674R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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