Product Name	INPP4B
Chinese Name	聚磷酸肌醇磷酸酶4B抗体
Alias	Inositol polyphosphate 4 phosphatase, type II; 4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase, type II; Inositol polyphosphate 4 phosphatase, type II, 105kDa; Inositol polyphosphate 4-phosphatase type II; INP4B_HUMAN; Inpp4b; MGC132014; Type II inositol 3,4 bisphosphate 4 phosphatase; Type II inositol-3.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Dog, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	105kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human INPP4B: 801-900/924
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008] Function: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Tissue Specificity: Widely expressed with highest levels occurring in the skeletal muscle and heart. Similarity: Belongs to the inositol-3,4-bisphosphate 4-phosphatase family. Contains 1 C2 domain. SWISS: O15327 Gene ID: 8821 Database links: Entrez Gene: 8821 Human Entrez Gene: 234515 Mouse Entrez Gene: 116699 Rat Omim: 607494 Human SwissProt: O15327 Human SwissProt: Q6P1Y8 Mouse SwissProt: Q9QWG5 Rat Unigene: 658245 Human Unigene: 324468 Mouse Unigene: 10829 Rat

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