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Product Name phospho-inaD (Thr666) Chinese Name 磷酸化inaD蛋白抗体 Alias inaD (phospho T666); p-inaD (phospho T666); Inactivation-no-after-potential D protein; inaD; INAD_DROME. Product Type Phosphorylated anti Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species Firefly, Fruit Fly, Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 74kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthesised phosphopeptide derived from Fruitfly inaD around the phosphorylation site of Thr666: KP(p-T)LR Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Involved in the negative feedback regulation of the light-activated signaling cascade in photoreceptors through a calcium-mediated process. Interacts with tetrapeptide ligand located in C-terminal sequence of 3 key components of the visual cascade, tethering them and forming a macromolecular signaling phototransduction complex.
Function:
Involved in the negative feedback regulation of the light-activated signaling cascade in photoreceptors through a calcium-mediated process. Interacts with tetrapeptide ligand located in C-terminal sequence of 3 key components of the visual cascade, tethering them and forming a macromolecular signaling phototransduction complex.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed in rhabdomeres of the compound eyes and ocelli.
Post-translational modifications:
Phosphorylated by inaC.
Similarity:
Contains 5 PDZ (DHR) domains.
SWISS:
Q24008
Gene ID:
37629
Database links:Entrez Gene: 37629 Fruit fly (Drosophila melanogaster)
SwissProt: Q24008 Fruit fly (Drosophila melanogaster)
Unigene: 2964 Fruit fly (Drosophila melanogaster)
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