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Product Name Integrin alpha 9 Chinese Name 整合素α9抗体 Alias Alpha RLC; Alpha RLC; Integrin alpha 4 like; Integrin alpha RLC; Integrin alpha-9; Integrin alpha-RLC; ITA9_HUMAN; ITGA 4L; ITGA 9; ITGA4L; ITGA9; RLC. literatures Specific References (1) | SL16612R has been referenced in 1 publications.[IF=2.741] Cui, Xiyao. et al. TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J. BMC VET RES. Bmc Vet Res. 2022 Dec;18(1):1-8 WB ; Chicken.Research Area Tumour Cell biology Signal transduction glycoprotein The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 112kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Integrin alpha 9: 51-150/1035 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
Function:
Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin.
Subcellular Location:
Membrane.
Tissue Specificity:
In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers.
Similarity:
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
SWISS:
Q13797
Gene ID:
3680
Database links:Entrez Gene: 3680 Human
Entrez Gene: 104099 Mouse
Omim: 603963 Human
SwissProt: Q13797 Human
Unigene: 113157 Human
Unigene: 335520 Mouse
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