Product Name	TRAP alpha
Chinese Name	易位相关蛋白α/TRAP-α抗体
Alias	DKFZp781N23103; FLJ14232; FLJ22100; FLJ23034; FLJ78242; FLJ93042; PGP35; Signal sequence receptor alpha; Signal sequence receptor alpha subunit; Signal sequence receptor subunit alpha; SSR 1; SSR alpha; SSR-alpha; SSR1; SSRA_HUMAN; SSRalpha; Translocon associated protein alpha; Translocon associated protein alpha subunit; Translocon associated protein subunit alpha; Translocon-associated protein subunit alpha; TRAP a; TRAP-alpha; TRAPa; TRAPalpha.
literatures	Specific References  (1)     |     SL16579R has been referenced in 1 publications. [IF=7.419] Jingyuan Wen. et al. Qiangguyin inhibited fat accumulation in OVX mice through the p38 MAPK signaling pathway to achieve anti-osteoporosis effects. BIOMED PHARMACOTHER. 2023 Feb;158:114122  IHC ;  Mouse.   PubMed:36566522
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	30kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TRAP alpha: 201-286/286
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. [provided by RefSeq, Jul 2008] Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Belongs to the TRAP-alpha family. SWISS: P43307 Gene ID: 6745 Database links: Entrez Gene: 6745 Human Entrez Gene: 107513 Mouse Entrez Gene: 361233 Rat Omim: 600868 Human SwissProt: P43307 Human SwissProt: Q9CY50 Mouse SwissProt: Q7TPJ0 Rat Unigene: 114033 Human Unigene: 426670 Mouse Unigene: 490298 Mouse Unigene: 123918 Rat

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