Product Name	TRAM1
Chinese Name	相关易位膜蛋白1抗体
Alias	PNAS 8; PNAS8; PRO1292; TRAM 1; TRAM; TRAM1_HUMAN; TRAMP; Translocating chain associated membrane protein 1; Translocating chain associating membrane protein; Translocation associated membrane protein 1; Translocation associating membrane protein 1.
Research Area	Cell biology  Signal transduction  Cell type markers
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	43kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TRAM1: 61-160/374
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	TRAM1 belongs to the TRAM family. It stimulates or is required for the translocation of secretory proteins across the endoplasmic reticulum membrane. Function: Stimulatory or required for the translocation of secretory proteins across the ER membrane. Subunit: Interacts with human cytomegalovirus/HHV-5 protein US2. Subcellular Location: Endoplasmic reticulum membrane; Multipass membrane protein Similarity: Belongs to the TRAM family. Contains 1 TLC (TRAM/LAG1/CLN8) domain. SWISS: Q15629 Gene ID: 23471 Database links: Entrez Gene: 23471 Human Omim: 605190 Human SwissProt: Q15629 Human
Product Picture	Tissue/cell: Human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-TRAM1 Polyclonal Antibody, Unconjugated(SL16565R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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