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Product Name ZYG11BL Chinese Name ZYG11BL蛋白抗体 Alias C9orf60; chromosome 9 open reading frame 60; homolog of Zyg 11; Hzyg; Protein zer-1 homolog; zer 1 homolog (C elegans); ZER1; ZER1_HUMAN; ZYG; zyg 11 homolog B (C elegans) like; Zyg 11 homolog B like protein; ZYG homolog; Zyg-11 homolog B-like protein. Research Area Cell biology Signal transduction Epigenetics Ubiquitin Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 88kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZYG11BL: 21-120/766 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012]
Function:
Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.
Tissue Specificity:
Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.
Similarity:
Belongs to the zyg-11 family.
Contains 5 ARM repeats.
Contains 3 LRR (leucine-rich) repeats.
SWISS:
Q7Z7L7
Gene ID:
10444
Database links:Entrez Gene: 10444 Human
Entrez Gene: 227693 Mouse
SwissProt: Q7Z7L7 Human
SwissProt: Q80ZJ6 Mouse
Unigene: 147950 Human
Unigene: 44526 Mouse
Unigene: 488942 Mouse
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