Product Name	GRWD1
Chinese Name	GRWD1蛋白抗体
Alias	CDW4; CUL4 and DDB1 associated WDR protein 4; Glutamate rich WD repeat containing 1; Glutamate rich WD repeat containing protein 1; Glutamate rich WD repeat protein GRWD; Glutamate-rich WD repeat-containing protein 1; GRWD 1; GRWD; grwd1; GRWD1_HUMAN; KIAA1942; Regulator of ribosome biogenesis 1 homolog; RRB 1; RRB1; WD repeat domain 28; WDR 28; WDR28.
Research Area	Cell biology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	49kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GRWD1: 301-400/446
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012] Subunit: Interacts with METTL18. Subcellular Location: Nucleus, nucleolus. Similarity: Contains 5 WD repeats. SWISS: Q9BQ67 Gene ID: 83743 Database links: Entrez Gene: 468939 Chimpanzee Entrez Gene: 540739 Cow Entrez Gene: 83743 Human Entrez Gene: 612058 Dog Entrez Gene: 101144842 Gorilla Entrez Gene: 100733019 Guinea pig Entrez Gene: 100051020 Horse Entrez Gene: 100386385 Marmoset (common) Entrez Gene: 100441405 Orangutan Entrez Gene: 717966 Rhesus monkey Omim: 610597 Human SwissProt: Q1JQD2 Cow SwissProt: Q9BQ67 Human Unigene: 400625 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GRWD1) Polyclonal Antibody, Unconjugated (SL16328R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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