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Product Name GRRP1 Chinese Name GRRP1蛋白抗体 Alias FAM110D; Family with sequence similarity 110, member D; Glycine/arginine-rich protein 1; GRPP1_HUMAN; GRRP1; Protein FAM110D; RP11-96L14.5. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 29kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GRRP1: 51-150/271 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GRRP1 (glycine/arginine-rich protein 1), also known as FAM110D, is a 271 amino acid protein encoded by a gene that maps to human chromosome 1p36.11 and mouse chromosome 4 D3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Similarity:
Belongs to the FAM110 family.
SWISS:
Q8TAY7
Gene ID:
79927
Database links:Entrez Gene: 79927 Human
Entrez Gene: 72690 Mouse
SwissProt: Q8TAY7 Human
SwissProt: Q80X91 Mouse
Unigene: 694119 Human
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