Product Name	FRYL
Chinese Name	FRYL蛋白抗体
Alias	2010313D22Rik; 2310004H21Rik; 2510002A14Rik; 9030227G01Rik; AF4P12; AI930088; ALL fused gene from chromosome 4p12; ALL1-fused gene from chromosome 4p12 protein; DKFZp686E205; FLJ161772; FRYL_HUMAN; FRY like; Furry homolog like (Drosophila); Furry homolog like; Furry like; KIAA0826; mKIAA0826; Protein furry homolog-like.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	339kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FRYL: 301-400/3013
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FRYL plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis. It regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. FRYL May function as a transcriptional activator. Function: Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator. Tissue Specificity: Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin. DISEASE: Note=A chromosomal aberration involving FRYL is found in treatment-related acute lymphoblastic leukemia (ALL). Translocation t(4;11)(p12;q23) that forms a KMT2A/MLL1-FRYL fusion protein. Similarity: Belongs to the furry protein family. SWISS: O94915 Gene ID: 285527 Database links: Entrez Gene: 285527 Human Entrez Gene: 72313 Mouse SwissProt: O94915 Human

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