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Product Name FOXS1 Chinese Name 叉头蛋白S1抗体 Alias FKHL18; forkhead (Drosophila)-like 18; Forkhead box protein S1; Forkhead box S1; forkhead-like 18 (Drosophila); Forkhead-like 18 protein; Forkhead-related activator 10; Forkhead-related transcription factor 10; Forkhead-related transcription factor FREAC-10; Foxs1; FOXS1_HUMAN; FREAC 10; FREAC-10; FREAC10; MGC4544. Research Area Cell biology immunology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 36kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FOXS1: 1-100/330 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]
Function:
Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature
Subcellular Location:
Nucleus.
Similarity:
Contains 1 fork-head DNA-binding domain.
SWISS:
O43638
Gene ID:
2307
Database links:Entrez Gene: 2307 Human
Omim: 602939 Human
SwissProt: O43638 Human
Unigene: 516971 Human
Product Picture Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-FOXS1 Polyclonal Antibody, Unconjugated(SL16177R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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