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Product Name FCRLB Chinese Name FCRLB蛋白抗体 Alias Fc receptor homolog expressed in B cells protein 2; Fc receptor like B; Fc receptor like mucin like 2; Fc receptor like protein 2; Fc receptor related Y; FCRL2; FCRLM2; FCRLY; Fcry; FCRLB_HUMAN; FLJ31052; FREB 2; FREB2; mFCRL2; RGD1563018; RP11-474I16.6. Research Area Cell biology immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FCRLB: 221-320/426 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]
Function:
FCRLB belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions.
Subcellular Location:
Cytoplasm. Endoplasmic reticulum. Note: Seems not to be secreted.
Tissue Specificity:
Expressed at low levels. Expressed in B-lymphocytes. Detected in tonsil, lung, kidney, spleen and placenta. Expressed by a small subset of germinal center B-cells in tonsils and by melanocytes (at protein level).
Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
Q6BAA4
Gene ID:
127943
Database links:Entrez Gene: 127943 Human
Omim: 609251 Human
SwissProt: Q6BAA4 Human
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