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Product Name IFNA13 Chinese Name Interferonα抗体 Alias IFL; IFN alpha; IFN-Alpha; IFN; IFNA; IFNA1; Interferon alpha 1; Interferon alpha 1/13; Interferon alpha 13; Interferon alpha D; Interferon alpha; Interferon alpha leukocyte; Interferon leukocyte; LeIF D; MGC138207; MGC138505; MGC138507; IFNA1 interferon, alpha 1; IFNA8_HUMAN; IFNA1_HUMAN; Interferon alpha-8; IFN-alpha-8; Interferon alpha-B; LeIF B; Interferon alpha-B2. Research Area Tumour immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 21kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IFN-Alpha: 161-189/189 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]
The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
Function:
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Subcellular Location:
Secreted.
Similarity:
Belongs to the alpha/beta interferon family.
SWISS:
P01562
Gene ID:
3439
Database links:Entrez Gene: 3439 Human
Entrez Gene: 3447 Human
Omim: 147660 Human
SwissProt: P01562 Human
Unigene: 37026 Human
Unigene: 533471 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFNA13) Polyclonal Antibody, Unconjugated (SL1578R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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