Product Name	GPR70
Chinese Name	G protein-coupled receptorTAS1R1蛋白抗体
Alias	G protein coupled receptor 70; G protein-coupled receptor 70; G-protein coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148;GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); seven transmembrane helix receptor; Sweet taste receptor T1r; T1R1; TAS1 R1; TAS1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR 1; TR1; TS1R1; TS1R1_HUMAN.
Research Area	Cell biology  immunology  Neurobiology  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	91kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPCR TAS1R1: 431-530/841 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Subunit: Forms heterodimers with TAS1R3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. SWISS: Q7RTX1 Gene ID: 80835 Database links: Entrez Gene: 80835 Human Entrez Gene: 110326 Mouse Entrez Gene: 29407 Rat Omim: 606225 Human SwissProt: Q7RTX1 Human SwissProt: Q99PG6 Mouse SwissProt: Q9Z0R8 Rat Unigene: 124574 Human Unigene: 29232 Mouse Unigene: 92309 Rat

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