Product Name	GPCR RTA/MRGPRF
Chinese Name	G protein-coupled receptorRTA蛋白抗体
Alias	GPR140; GPR168; MGC21621; mrgF; MRGPRF; RTA; MRGRF_HUMAN.
Research Area	Cell biology  immunology  Neurobiology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPCR RTA: 51-150/343 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	MRGF is a 343 amino acid multi-pass membrane protein that functions as an orphan receptor. MRGF belongs to the G-protein coupled receptor 1 family and Mas subfamily, and is thought to have a role in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGF maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. SWISS: Q96AM1 Gene ID: 219928 Database links: Entrez Gene: 219928 Human Entrez Gene: 211577 Mouse Entrez Gene: 266762 Rat SwissProt: Q96AM1 Human SwissProt: Q8VCJ6 Mouse SwissProt: P23749 Rat

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