Product Name	GPR85
Chinese Name	G protein-coupled receptorGPR85蛋白抗体
Alias	GPR85; Probable G-protein coupled receptor 85; SREB; SREB2; Super conserved receptor expressed in brain 2; GPR85_HUMAN; GPCR 85.
Research Area	Cell biology  immunology  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	42kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPR85: 31-130/370 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR85 is a member of this family (subfamily Orphan-A). GPCR GPR85 has been reported to be expressed in several areas of human and rat CNS (Matsumoto et al., 2000), as well as in genital organs. ESTs have been isolated from B-cell/lung/testis, brain, testis, and embryo libraries, as well as many mouse tissue libraries. Function: Orphan receptor. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P60893 Gene ID: 54329 Database links: Entrez Gene: 417775 Chicken Entrez Gene: 54329 Human Entrez Gene: 64450 Mouse Entrez Gene: 100190819 Orangutan Entrez Gene: 64020 Rat Entrez Gene: 793299 Zebrafish Omim: 605188 Human SwissProt: P60893 Human SwissProt: P60894 Mouse SwissProt: Q5RBG7 Orangutan SwissProt: P60895 Rat SwissProt: Q9I919 Zebrafish Unigene: 152009 Human Unigene: 167625 Mouse Unigene: 53985 Rat

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