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Product Name GPR62 Chinese Name G protein-coupled receptorGPR62蛋白抗体 Alias GPCR GPR62; G-protein coupled receptor GPCR8; G-protein coupled receptor KPG_005; GPCR8; GPR62; hGPCR8; KPG_005; MGC26943; Probable G-protein coupled receptor 62; GPR62_HUMAN; GPCR 62. Research Area Cell biology immunology Neurobiology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Pig, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GPR62: 31-130/368 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GPR62 is a 368 amino acid protein encoded by the human GPR62 gene. GPR62 is an orphan receptor member of the G protein-coupled receptor 1 family. G protein-coupled receptors (GPCRs or GPRs) contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and its termination. GPR62 is expressed in brain tissue, most notably the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus.
Function:
Orphan receptor.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q9BZJ7
Gene ID:
118442
Database links:Entrez Gene: 118442 Human
Omim: 606917 Human
SwissProt: Q9BZJ7 Human
Unigene: 232213 Human
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