Product Name	C3orf23
Chinese Name	3号染色体开放阅读框23抗体
Alias	C3orf23; TCAIM_HUMAN; Chromosome 3 open reading frame 23; D9Ertd402e; DKFZp313N0621; FLJ41686; Hypothetical protein LOC285343; MGC119530; MGC119531; MGC119532; MGC119533; TOAG1; Tolerance associated gene 1; Uncharacterized protein C3orf23.
Research Area	Tumour  Cardiovascular  Cell biology  immunology  Developmental biology  Mitochondrion  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Rabbit, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	58kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human C3orf23
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	C3orf23 (chromosome 3 open reading frame 23), also known as FLJ41686, MGC119530, MGC119531, MGC119532, MGC119533 or DKFZp313N062, is a 496 amino acid protein that exists as four alternatively spliced isoforms. C3orf23 is encoded by a gene mapping to human chromosome 3p21.33. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. Function: May regulate T-cell apoptosis (By similarity). Subcellular Location: Mitochondrion (By similarity). SWISS: Q8N3R3 Gene ID: 285343 Database links: Entrez Gene: 285343 Human SwissProt: Q8N3R3 Human SwissProt: Q66JZ4 Mouse Unigene: 55131 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (human esophagus cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C3orf23) Polyclonal Antibody, Unconjugated (SL15169R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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