Product Name	Uteroglobin
Chinese Name	克拉拉细胞蛋白抗体
Alias	Clara cell protein 16; SCGB1A1; CC10; CCPBP; CCSP; UGB; UP-1; UP1; Secretoglobin, family 1A, member 1; PCB-binding protein; PCB-BP; UG; Clara cell phospholipid-binding; CC16; Clara cells 10 kDa secretory protein; Urinary protein 1; Urine protein 1; UTER_HUMAN; UTER_MOUSE; SCGB1A1.
literatures	Specific References  (3)     |     SL1487R has been referenced in 3 publications. [IF=11.864] Shibata T et al. Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization. J Clin Invest. 2020 Jun 1;130(6):3021-3037.  IHC-P ;  Mouse.   PubMed:32364537 [IF=5.923] Mohamed Elbadawy. et al. Establishment of Intestinal Organoid from Rousettus leschenaultii and the Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus. Int J Mol Sci. 2021 Jan;22(19):10763  IHC ;  Bat.   PubMed:34639103 [IF=3.12] Mori, Gentaro, et al. "The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri‐implant epithelium of rats." Clinical Oral Implants Research (2015).  IHC-P ;  Rat.   PubMed:25864924
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Mouse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	8.4kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Uteroglobin: 21-86/96
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq]. Function: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Subunit: Homodimer; antiparallel disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). Similarity: Belongs to the secretoglobin family. SWISS: Q06318 Gene ID: 22287 Database links: Entrez Gene: 7356 Human Entrez Gene: 22287 Mouse Entrez Gene: 25575 Rat Omim: 192020 Human SwissProt: P11684 Human SwissProt: Q06318 Mouse SwissProt: P17559 Rat Unigene: 523732 Human Unigene: 2258 Mouse Unigene: 2206 Rat Clara细胞分泌蛋白(CC16)具有明显的抗炎作用.
Product Picture	Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CC16/CCSP Polyclonal Antibody, Unconjugated(SL1487R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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