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Product Name phospho-EEF1A2(Ser358) Chinese Name 磷酸化翻译延伸因子EF-1 α2抗体 Alias EEF1A2 (phospho S358);p-EEF1A2 (phospho S358); eEF1A 2; eEF1A-2; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-2; EF1A; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 2; Eukaryotic elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; HS1; OTTHUMP00000031776; Statin like; Statin S1; Statin-S1; STN; STNL. Product Type Phosphorylated anti Research Area Cell biology Signal transduction transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 50kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised phosphopeptide derived from human EEF1A2 around the phosphorylation site of Ser358: GY(p-S)PV Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Location:
Nucleus.
Tissue Specificity:
Brain, heart, and skeletal muscle.
Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
SWISS:
Q05639
Gene ID:
1917
Database links:Entrez Gene: 1917 Human
Entrez Gene: 13628 Mouse
Entrez Gene: 101109898 Sheep
Entrez Gene: 380550 Xenopus laevis
Omim: 602959 Human
SwissProt: Q05639 Human
SwissProt: P62631 Mouse
Unigene: 433839 Human
Unigene: 2645 Mouse
Unigene: 9764 Rat
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