Product Name	EFCAB1
Chinese Name	EFCAB1蛋白抗体
Alias	EF-CAB1; EF-hand calcium binding domain 1; EF-hand calcium-binding domain-containing protein 1; EFCAB1; EFCB1_HUMAN.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human EFCAB1: 3-100/211
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The gene encoding EF-CAB1 (EF-hand calcium-binding domain-containing peptide protein 1) is located on the long arm of chromsome 8. This 211 amino acid protein contains 3 EF-hand domains, which are helix-loop-helix structures that are usually found in calcium binding proteins. Other well-studied calcium binding proteins that contain EF-hand motifs include calmodulin (CaM), Troponin C, myosin regulatory light chain (MYL) and S-100 proteins. Similarity: Contains 3 EF-hand domains. SWISS: Q9HAE3 Gene ID: 79645 Database links: Entrez Gene: 79645 Human Entrez Gene: 66793 Mouse Entrez Gene: 301957 Rat SwissProt: Q9HAE3 Human SwissProt: Q9D3N2 Mouse Unigene: 23245 Human

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