Product Name	DECR2
Chinese Name	过氧化物酶体2抗体
Alias	2 4 dienoyl CoA reductase 2; 2 4 dienoyl CoA reductase 2 peroxisomal; 2; 4-dienoyl-CoA reductase 2; 4-dienoyl-CoA reductase; DECR 2; Decr2; DECR2_HUMAN; EC 1.3.1.34; pDCR; Peroxisomal 2 4 dienoyl CoA reductase; Peroxisomal 2; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1.
Research Area	Cell biology  Cell type markers  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	31kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DECR2: 201-292/292
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DECR2 is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events. Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Subunit: Monomer, dimer and oligomer. Subcellular Location: Peroxisome. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. SWISS: Q9NUI1 Gene ID: 26063 Database links: Entrez Gene: 26063 Human Entrez Gene: 26378 Mouse Entrez Gene: 64461 Rat SwissProt: Q9NUI1 Human SwissProt: Q9WV68 Mouse SwissProt: Q9Z2M4 Rat Unigene: 628831 Human Unigene: 655999 Human Unigene: 292869 Mouse Unigene: 144598 Rat

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