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Product Name DDX47 Chinese Name ATP依赖RNA解旋酶DDX47抗体 Alias DDX47; DDX47_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 47; DEAD box protein 47; DKFZp564O176; E4 DBP; FLJ30012; HGNC:18682; HQ0256; MSTP162; Probable ATP dependent RNA helicase DDX47; Probable ATP-dependent RNA helicase DDX47. Research Area Cell biology Developmental biology transcriptional regulatory factor Binding protein Cell differentiation Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 50kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DDX47: 201-300/455 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Subcellular Location:
Nucleus; nucleolus.
Similarity:
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
SWISS:
Q9H0S4
Gene ID:
51202
Database links:Entrez Gene: 51202 Human
Entrez Gene: 67755 Mouse
SwissProt: Q9H0S4 Human
SwissProt: Q9CWX9 Mouse
Unigene: 719938 Human
Unigene: 166524 Mouse
Unigene: 73790 Rat
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