Product Name	DDX46
Chinese Name	ATP依赖RNA解旋酶DDX46抗体
Alias	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; Probable ATP dependent RNA helicase DDX46; PRP5 homolog; DDX46_HUMAN; Prp5 like DEAD-box protein; PRPF5; RNA helicase.
Research Area	Cell biology  Binding protein  Cell differentiation  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	117kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DDX46: 251-350/1031
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. [provided by RefSeq, Jul 2008] Function: Plays an essential role in splicing, either prior to, or during splicing A complex formation. Subcellular Location: Nucleus speckle. Nucleus, Cajal body. SWISS: Q7L014 Gene ID: 9879 Database links: Entrez Gene: 9879 Human Entrez Gene: 212880 Mouse Entrez Gene: 245957 Rat SwissProt: Q7L014 Human SwissProt: Q569Z5 Mouse SwissProt: Q62780 Rat Unigene: 406549 Human Unigene: 202725 Mouse Unigene: 3436 Rat

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