Product Name	Histone H1t
Chinese Name	组蛋白H1抗体
Alias	H1 histone family, member T (testis specific); H1FT; H1T; H1T_HUMAN; Hist1h1t; Histone cluster 1, H1t; Testicular H1 histone.
literatures	Specific References  (1)     |     SL1413R has been referenced in 1 publications. [IF=3.743] Liu B et al. The atherosclerosis-ameliorating effects and molecular mechanisms of BuYangHuanWu decoction. Biomed Pharmacother. 2019 Dec 27;123:109664.  WB ;  Rat.   PubMed:31887542
Research Area	Tumour  immunology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Testicular H1 histone: 51-207/207
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. Subcellular Location: Nucleus. Chromosome. Post-translational modifications: Phosphorylated in early spermatids. Similarity: Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain. SWISS: P22492 Gene ID: 3010 Database links: Entrez Gene: 3010 Human Omim: 142712 Human SwissProt: P22492 Human Unigene: 533293 Human
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- Histone H1t (SL1413R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 22 kD Sample: Testis (Rat) Lysate at 40 ug Primary: Anti- Histone H1t (SL1413R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 22 kD

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