Product Name	CEP192
Chinese Name	中心体蛋白192抗体
Alias	Centrosomal protein 192kDa; Centrosomal protein of 192 kDa; Cep192; KIAA1569; PP8407; PPP1R62; CE192_HUMAN; Protein phosphatase 1, regulatory subunit 62.
Research Area	Tumour  Cell biology  Signal transduction  Cell type markers  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	279kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEP192: 51-150/2537
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Subcellular Location: Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Post-translational modifications: Hydroxylation by PHD1/EGLN2 at Pro-1717 promotes ubiquitination. Ubiquitinated by a SCF(SKP2) complex following proline hydroxylation. SWISS: Q8TEP8 Gene ID: 55125 Database links: Entrez Gene: 55125 Human SwissProt: Q8TEP8 Human Unigene: 100914 Human
Product Picture	Tissue/cell: human liver cancer; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CEP192 Polyclonal Antibody, Unconjugated(SL13856R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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