Product Name	Centrin-1+Centrin-2
Chinese Name	中心体蛋白1+2抗体
Alias	Caltractin; Caltractin isoform 2; CEN 1; CEN1; Centrin EF hand protein 1; Centrin-1; Centrin1; CETN 1; CETN; CETN1; CETN1_HUMAN; EF hand protein 1; 20kD calcium binding protein; CALT; caltractin; Caltractin isoform 1; CEN2; centrin; centrin, EF hand protein, 2; Centrin-2; Centrin2; CETN2; CETN2_HUMAN; EF hand protein 2; EF-hand protein.
Research Area	Cell biology  Signal transduction  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	20kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Centrin 1: 101-172/172
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jul 2008] Function: Plays a fundamental role in microtubule-organizing center structure and function. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Centrosome of interphase and mitotic cells. Similarity: Belongs to the centrin family. Contains 4 EF-hand domains. SWISS: Q12798 Gene ID: 1068 1069 Database links: Entrez Gene: 1068 Human Entrez Gene: 512850 Cow Omim: 603187 Human SwissProt: Q32LE3 Cow SwissProt: Q12798 Human Unigene: 122511 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Centrin-1+Centrin-2) Polyclonal Antibody, Unconjugated (SL13848R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Centrin-1+Centrin-2) Polyclonal Antibody, Unconjugated (SL13848R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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