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Product Name CENPBD1 Chinese Name CENPBD1蛋白抗体 Alias CENP1_HUMAN; CENPB DNA binding domains containing 1; CENPB DNA-binding domain-containing protein 1; CENPBD1; FLJ23771; FLJ31569; MGC13198; MGC16385. Research Area Tumour Cell biology Neurobiology Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 21kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CENPBD1: 21-120/187 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CENPBD1 is a 187 amino acid nuclear protein that contains one HTH CENPB-type DNA-binding domain and a HTH psq-type DNA-binding domain. The gene encoding CENPBD1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 HTH CENPB-type DNA-binding domain.
Contains 1 HTH psq-type DNA-binding domain.
SWISS:
B2RD01
Gene ID:
92806
Database links:Entrez Gene: 92806 Human
SwissProt: B2RD01 Human
Unigene: 513832 Human
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