Product Name	CEMP1
Chinese Name	牙骨质蛋白1抗体
Alias	Cementoblastoma-derived protein 1; Cementum protein 1; Cementum protein 23; CEMP1; CEMP1_HUMAN; CP-23; CP23.
Research Area	Tumour  Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEMP1: 151-247/247
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	A mineralized connective tissue known as cementum covers the root surfaces of teeth and is required for maturation of periodontal tissue. CEMP1 (cementum protein 1), also designated CP23 or cementoblastoma-derived protein 1, is a 247 amino acid nuclear and cytoplasmic protein that is thought to regulate cementoblast behavior. Expressed specifically in periodontal ligament and cementum, CEMP1 may play a role in differentiation and mineralization of non-osteogenic cells. The gene encoding CEMP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in periodontal ligament, cementum, cementoblasts and cementoblastoma. SWISS: Q6PRD7 Gene ID: 752014 Database links: Entrez Gene: 752014 Human Omim: 611113 Human SwissProt: Q6PRD7 Human Unigene: 433499 Human Unigene: 737156 Human Unigene: 743305 Human

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