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Product Name SPANXB1 Chinese Name Tumour/睾丸抗原11.2抗体 Alias Cancer/testis antigen 11.2; Cancer/testis antigen family 11, member 2; CT11.2; hCG2036708; Nuclear associated protein SPAN Xb; Nuclear-associated protein SPAN-Xb; Nuclear-associated protein SPAN-Xf; SPAN Xb protein; SPAN Xf; SPANX; SPANX B; SPANX C; SPANX F; SPANX family member B/F; SPANX family, member B1; SPANX family, member B2; SPANX family, member F1; SPANX-B; SPANX-F; SPANXB; SPANXB2; SPANXF; SPANXF1; Sperm protein associated with the nucleus on the X chromosome B/F; Sperm protein associated with the nucleus, X chromosome, family; Sperm protein associated with the nucleus, X chromosome, family member B1; Sperm protein associated with the nucleus, X chromosome, family member B2; SPNXB_HUMAN. Research Area Tumour Cell biology Developmental biology Stem cells transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 12kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPANXB1: 1-80/103 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.
Subcellular Location:
Cytoplasm. Nucleus. Associated with nuclear craters.
Tissue Specificity:
Detected in testis and sperm.
Similarity:
Belongs to the SPAN-X family.
SWISS:
Q9NS25
Gene ID:
71490
Database links:Entrez Gene: 171490 Human
Entrez Gene: 100133171 Human
Entrez Gene: 728695 Human
Omim: 300669 Human
SwissProt: Q9NS25 Human
Unigene: 434105 Human
Unigene: 711489 Human
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