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Rabbit Anti-ZBTB6 antibody
Rabbit Anti-ZBTB6 antibody
ZBTB 6; ZBTB6; ZBTB6_HUMAN; ZID; Zinc finger and BTB domain containing protein 6; Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain; ZNF 482; ZNF482.
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Details

Product Name ZBTB6
Chinese Name Zinc finger proteinZBTB6抗体
Alias ZBTB 6; ZBTB6; ZBTB6_HUMAN; ZID; Zinc finger and BTB domain containing protein 6; Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain; ZNF 482; ZNF482.  
Research Area Cell biology  immunology  transcriptional regulatory factor  Zinc finger protein  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 48kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZBTB6/ZNF482: 351-424/424 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed with highest levels in brain.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 4 C2H2-type zinc fingers.

SWISS:
Q15916

Gene ID:
10773

Database links:

Entrez Gene: 10773 Human

Entrez Gene: 241322 Mouse

Entrez Gene: 366029 Rat

Omim: 605976 Human

SwissProt: Q15916 Human

SwissProt: Q8K088 Mouse

Unigene: 654596 Human

Unigene: 330182 Mouse

Unigene: 39069 Rat



Product Picture
Sample:
HepG2 Cell (Human) Lysate at 30 ug
Primary: Anti- ZBTB6 (SL13582R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kD
Observed band size: 48 kD

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