Product Name	ZBTB5
Chinese Name	Zinc finger proteinZBTB5抗体
Alias	5930421I10; 9430083K24Rik; AI646847; Expressed in brain and neural tube; KIAA0354; mKIAA0354; OTTMUSP00000007812; OTTMUSP00000007813; OTTMUSP00000007814; RP11-397D12.5; RP23-218A4.2; Transcription factor ZNF POZ; Zbtb5; ZBTB5_HUMAN; Zinc finger and BTB domain containing protein 5; Zinc finger and BTB domain-containing protein 5.
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	74kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZBTB5: 581-677/677
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Contains 1 BTB (POZ) domain. Contains 2 C2H2-type zinc fingers. SWISS: O15062 Gene ID: 9925 Database links: Entrez Gene: 9925 Human Entrez Gene: 230119 Mouse Entrez Gene: 298084 Rat SwissProt: O15062 Human SwissProt: Q7TQG0 Mouse Unigene: 161276 Human
Product Picture	Sample:MCF-7 (Human)cell Lysate at 40 ug Primary: Anti-ZBTB5(SL13581R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 74kD Observed band size: 75kD

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