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Rabbit Anti-ZBTB43 antibody
Rabbit Anti-ZBTB43 antibody
RP11489N222; ZBT43_HUMAN; ZBTB22B; ZBTB43; Zinc Finger And BTB Domain Containing 43; Zinc finger and BTB domain-containing protein 22B; Zinc finger and BTB domain-containing protein 43; Zinc Finger Protein 297B; ZnF-x; ZNF297B; ZNFX.
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  • NO.:SL13578R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:28
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Details

Product Name ZBTB43
Chinese Name Zinc finger protein297B抗体
Alias RP11489N222; ZBT43_HUMAN; ZBTB22B; ZBTB43; Zinc Finger And BTB Domain Containing 43; Zinc finger and BTB domain-containing protein 22B; Zinc finger and BTB domain-containing protein 43; Zinc Finger Protein 297B; ZnF-x; ZNF297B; ZNFX.  
Research Area Cell biology  transcriptional regulatory factor  Zinc finger protein  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 53kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZBTB43: 351-450/467 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 43 (ZBTB43), also known as ZNF297B or ZBTB22B, is a 467 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB43 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain and the interaction of ZBTB43 with BDP1 suggest that ZBTB43 functions as a transcription regulator.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 3 C2H2-type zinc fingers.

SWISS:
O43298

Gene ID:
23099

Database links:

Entrez Gene: 23099 Human

Entrez Gene: 71834 Mouse

Entrez Gene: 311872 Rat

SwissProt: O43298 Human

SwissProt: Q9DAI4 Mouse

SwissProt: Q5PQT4 Rat

Unigene: 355581 Human

Unigene: 44186 Mouse



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