TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ZA20D3 Chinese Name Zinc finger protein20D3抗体 Alias 3110005P07Rik; Associated with PRK1 protein; AWP1; DKFZp564F2116; fb11b11; Za20d3 zinc finger A20 domain containing 3; ZFAN6_HUMAN; ZA20D3; ZFAND5B; AN1-type zinc finger protein 6; Zinc finger A20 domain-containing protein 3 Research Area Cell biology Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 23kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZA20D3: 111-208/208 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZA20D3 is a zinc-finger protein located on chromosome 15. It is associated with PRK1.
Function:
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes
Subunit:
Interacts with PKN1 (By similarity). Interacts with TRAF2. Interacts with mono- and polyubiquitin. Interacts with PEX6. Interacts with PEX5 (Cys-linked ubiquitinated) (By similarity).
Subcellular Location:
Cytoplasm
Tissue Specificity:
Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta.
Similarity:
Contains 1 A20-type zinc finger.
Contains 1 AN1-type zinc finger.
SWISS:
Q6FIF0
Gene ID:
54469
Database links:Entrez Gene: 54469 Human
Entrez Gene: 65098 Mouse
Omim: 610183 Human
SwissProt: Q6FIF0 Human
SwissProt: Q9BQF7 Human
SwissProt: Q9DCH6 Mouse
Unigene: 306329 Human
Unigene: 209349 Mouse
Unigene: 130357 Rat
Scan Wechat Qrcode