Product Name	ZBT24
Chinese Name	Zinc finger protein450抗体
Alias	ZBTB24; BIF1; ICF2; OTTHUMP00000016968; POZ (BTB) and AT hook containing zinc finger 2; ZBT24_HUMAN; Zbtb24; Zinc finger and BTB domain-containing protein 24; Zinc finger protein 450; ZNF45; PATZ2.
Research Area	Cell biology  Signal transduction  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	78kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZBT24: 451-550/697
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro. [provided by RefSeq, Aug 2011] Function: May be involved in BMP2-induced transcription. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed, with highest levels in naive B-cells. DISEASE: Immunodeficiency-centromeric instability-facial anomalies syndrome 2 (ICF2) [MIM:614069]: A rare disorder characterized by a variable immunodeficiency resulting in recurrent infections, facial anomalies, and branching of chromosomes 1, 9, and 16. Other variable symptoms include growth retardation, failure to thrive, and psychomotor retardation. Laboratory studies show limited hypomethylation of DNA in a small fraction of the genome in some, but not all, patients. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 A.T hook DNA-binding domain. Contains 1 BTB (POZ) domain. Contains 8 C2H2-type zinc fingers. SWISS: O43167 Gene ID: 9841 Database links: Entrez Gene: 9841 Human Omim: 614064 Human SwissProt: O43167 Human Unigene: 409876 Human

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