Product Name	GBP7
Chinese Name	G蛋白Binding protein7抗体
Alias	GBP 7; GBP4L; GTP binding protein 7; Guanine nucleotide binding protein 7; Guanylate binding protein 4 like; Guanylate binding protein 7; GBP7_HUMAN; Guanylate-binding protein 7; GTP-binding protein 7; GBP-7; Guanine nucleotide-binding protein 7; Guanylate-binding protein 4-like.
Research Area	Cell biology  Neurobiology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	73kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GBP7: 451-550/638
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP. Function: Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the GBP family. SWISS: Q8N8V2 Gene ID: 388646 Database links: Entrez Gene: 388646 Human Entrez Gene: 229900 Mouse Omim: 612468 Human SwissProt: Q8N8V2 Human SwissProt: Q91Z40 Mouse

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