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Product Name GBP6 Chinese Name G蛋白Binding protein6体 Alias DKFZp686G0786; FLJ39135; GBP 6; GBP-6; GBP6; GBP6_HUMAN; GTP binding protein 6; GTP-binding protein 6; Guanine nucleotide binding protein 6; Guanine nucleotide-binding protein 6; Guanylate binding protein 6; Guanylate binding protein family member 6; Guanylate-binding protein 6; GTP-binding protein 6. Research Area Tumour Cell biology Neurobiology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 72kDa Cellular localization Extracellular matrix Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GBP6: 331-430/633 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GBP6 is a 633 amino acid protein that exists as two alternatively spliced isoforms belonging to the GBP family. GBP6 binds GTP, GDP and GMP, and is encoded by a gene that maps to human chromosome 1p22.2. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Function:
Binds GTP, GDP and GMP.
Similarity:
Belongs to the GBP family.
SWISS:
Q6ZN66
Gene ID:
163351
Database links:Entrez Gene: 163351 Human
Entrez Gene: 100702 Mouse
Omim: 612467 Human
SwissProt: Q6ZN66 Human
Unigene: 254338 Human
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